Artificial active

Consumption of artificial sweeteners increases the risk of cancer: study | Bangalore News

Bengaluru: A French population-based study found that high consumption of artificial sweeteners leads to a 13% higher cancer risk compared to no consumption.
The study, conducted from 2009 to 2021 and involving 1,02,865 adults, highlighted the risk associated with the artificial sweeteners aspartame and acesulfame potassium used around the world. Bengaluru doctors say the study underscores the need to reevaluate the use of food additive sweeteners by global health agencies. “Artificial sweeteners and cancer risk: results from the NutriNet-Sante population-based cohort study” was recently published in the international journal Plos Medicine.
Of the total cohort studied, non-consumers of artificial sweetener were 64,892 (63%), low consumers 18,986 (18.5%) and high consumers 18,987 (18.5%). During follow-up, a total of 3,358 cases of cancer were diagnosed, of which 982 were breast cancer, 403 prostate and 2,023 obesity-related. The mean age at diagnosis was 59.5 years (+/- 12 years).
The study indicates that compared to non-consumers, high artificial sweetener consumers had a higher overall cancer risk and the hazard ratio was 1:13. Consumption of artificial sweeteners was positively associated with overall cancer risk. Artificial sweeteners were consumed by nearly 37% of participants. Compared to non-drinkers, high drinkers included more women, a younger population, smokers, less physically active people, more educated people, and more likely to have prevalent diabetes.
According to Dr. US Vishal Rao, Dean and Director, Head-Neck Oncology, HCG Cancer Center, experimental studies have so far only suggested the carcinogenicity of artificial sweeteners and strong epidemiological evidence has been lacking. “Now, a key cohort study has found that higher consumption of artificial sweeteners, specifically aspartame and acesulfame potassium, results in a 13% higher overall cancer risk compared to no consumption. Higher consumption of aspartame was found to be linked to a 22% higher overall cancer risk and a 15% higher obesity-related cancer risk,” Dr. Rao said.
“The safety of food additives such as artificial sweeteners widely used in snacks and beverages as an alternative to added sugar had been the subject of debate, and conclusions regarding their role in the etiology of various diseases were highly conflicting. is time to re-evaluate it further,” he said.
Dr Subrata Das, Senior Consultant Internal Medicine and Diabetology, Sakra World Hospital, said: “Certain biochemical amino acids and protein components may increase the risk of cancer. When the denominator (one lakh and more) is higher, the statistical significance is higher and hence the study for more than 11 years is interesting.
Dr. Das added that there is a myth that sugar-free drinks containing artificial sugars contain fewer calories and therefore many consume them.
However, according to Dr. C Ramachandra, director of the Kidwai Memorial Institute of Oncology, the study does not provide level 1 evidence to say that artificial sugars cause cancer as in the case of tobacco consumption. “This is only a predictive study, which needs to be further proven by randomized control studies,” he said.
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